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Roberto Pacifici

Roberto Pacifici, MD

4.8174 ratings

Endocrinology

Telehealth Visits Available
Video Visit
Need help scheduling? Call (404) 778-3280

Highlights

Languages

  • English
  • Italian

About Roberto Pacifici

Emory Affiliation

Emory Clinic - School of Medicine Faculty
Emory Healthcare Network
Emory Physician Group Practice

Academic Title

Professor

Garland Herndon Professor of Medicine

Year Started Practicing

1988

About the Provider

Dr. Pacifici is the director of the Division of Endocrinology. The Pacifici laboratory has pioneered the field of osteoimmunology and osteomicrobiology. The current main focus of the laboratory is the role of the microbiome in bone in health and disease. We are also interested in the mechanism of action of probiotics in bone. The laboratory is specialized in conducting in vivo studies in mice treated with PTH or subjected to ovariectomy.  We use genetic models, retroviral transduction, bone marrow transplantation, T cell transfer and in vivo treatments with hormones, cytokines,  antibodies and probiotics.  Typical end points include sophisticated flow cytometric analysis of bone marrow cells and microCT and histomorphometric analysis of bone structure.  The lab is equipped with in vivo and in vitro microCT scanners. We have been the first to recognize that T cells play a pivotal role in the mechanism of action of estrogen and PTH in bone by regulating osteoclast and osteoblast development and function. More recently we have shown that the gut microbiome plays a role in mediating the skeletal response to estrogen deficiency and PTH.  We have shown that mice lacking T cells are protected against the bone loss induced by estrogen deficiency and hyperparathyroidism.  We have has also shown that T cells regulate the number and function of mesenchymal stem cells. We have investigated the mechanism by which T cells mediate the expansion of hemopoietic stem cells caused by estrogen deficiency and PTH.  Another main focus is to understand why “intermittent” PTH treatment causes bone anabolism while “continuous” PTH treatment causes bone loss. We hypothesize that the response to PTH depends on the effects of this hormone on T cell production of Wnt10b and TNF. We are currently investigating the mechanism of action of probiotics in bone, and conducting a clinical trial to determine the efficacy of the probiotic VSL#3 in preventing postmenopausal bone loss. The Pacifici laboratory is currently supported by 3 RO-1 grants, 1 DOD grant and a T32 grant. Employment 2003 - current  - Division Director; Endocrinology and Metabolism  Herndon Professor of Medicine Department of Medicine, Emory University School of Medicine 2002 - 2003 -  Professor of Radiology, Mallinkrodt Institute of Radiology 2000 - 2003 - Sydney M. and Stella H. Shoenberg Professor of Medicine Division of Bone and Mineral Metabolism,  Washington University School of Medicine 1993 - 2000 - Associate Professor of Medicine, Washington University School of Medicine 1995 - 2000 - Assistant Professor of Radiology,  Mallinkrodt Institute of Radiology 1988 - 1993 - Assistant Professor of Medicine,  Washington University School of Medicine 1984 - 1988 -  Fellowship in Endocrinology and Metabolism, Div.of Bone & Mineral Metabolism, The Jewish Hospital of St. Louis at the Washington University Medical School

Interpretive Services

To provide the highest quality of care, interpreter services may be utilized to ensure proper communication of medical information for deaf, hard-of-hearing, and non-English speaking patients or family members.

Locations

  1. Emory Clinic at 1365 Clifton Road
    • 1365 Clifton Road Northeast, Bldg A, Fl 3, Atlanta, GA 30322
    • Get Directions
  2. Emory Saint Joseph's Hospital Campus
    • 5671 Peachtree Dunwoody Road, Fl 2, Ste 210, Atlanta, GA 30342
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Expertise

Education

  • Fellowship: Washington University School of Medicine, Endocrinology, 1988
  • Medical Education: Perugia University School of Medi-Italy, 1984
  • Medical Education: Perugia University School of Medi-Italy, MD, 1981

Ratings & Reviews

4.8 out of 5

174 ratings

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Provider showed concern
Provider explained things clearly
Provider discussed treatment options
Provider included you in decisions
Likelihood of recommending this provider
Search reviews
    5 out of 5 stars
    Reviewed on 4/3/2026

    Dr. P. Is a wonderful doctor, very caring, explains everything thoroughly.

    5 out of 5 stars
    Reviewed on 4/1/2026

    Clearly a contemplative physician.

    5 out of 5 stars
    Reviewed on 4/1/2026

    Dr. Roberto Pacifici Is an excellent physician, answered any questions I had. Explained test results & future plans. Can tell he cares about his patients.

    5 out of 5 stars
    Reviewed on 3/26/2026

    The doctor was kind, caring, extremely knowledgeable and approachable.

    5 out of 5 stars
    Reviewed on 3/14/2026

    Doctor ordered necessary tests to get my health back in good condition.

    3 out of 5 stars
    Reviewed on 2/20/2026

    VERY brief appointment time and summary notes were partly a year old

    5 out of 5 stars
    Reviewed on 2/20/2026

    Dr. Pacifici is amazing! Extremely thorough and patient. He is always warm, friendly, professional, and compassionate. I always leave feeling hopeful and motivated to do everything he recommends!

    5 out of 5 stars
    Reviewed on 1/15/2026

    I would happily recommend Dr. Pacifici, except for his limited availability

    5 out of 5 stars
    Reviewed on 1/10/2026

    Dr.Pacifici is professional and listen to the patient

    5 out of 5 stars
    Reviewed on 12/12/2025

    Dr Pacifici was very knowledgeable, he listened to my problems he took time to explain my condition to me and gave me his expert advice. He was very personable and spent a good amount of time with me. I left feeling confident about the treatment we chose

    5 out of 5 stars
    Reviewed on 12/12/2025

    Wish all offices and doctors were like this!!

    5 out of 5 stars
    Reviewed on 10/9/2025

    I would have liked to have had my apple with Dr Pacifici after the bone density test but could not obtain the bone density order in time.

    5 out of 5 stars
    Reviewed on 10/9/2025

    I HAD A GREAT EXPERIENCE AT EMORY ON CLIFTON RD.

    5 out of 5 stars
    Reviewed on 9/27/2025

    Dr. Pacifici is great!

    5 out of 5 stars
    Reviewed on 9/12/2025

    Excellent attention and I did not feel rushed at all.

    5 out of 5 stars
    Reviewed on 9/12/2025

    Dr Pacifici explained the information from the bone scan snd explained an upper spinal curverature.

    5 out of 5 stars
    Reviewed on 8/31/2025

    I feel very lucky I had Dr. Pacifici as my doctor for many years

    5 out of 5 stars
    Reviewed on 8/28/2025

    Dr Pacifici is always kind thorough and explains to me about my condition. He came in very happy and proud of me for improving greatly. He is consistent with compassion , listening and supportive words. So happy to see him each year. Excellent Doctor

    5 out of 5 stars
    Reviewed on 8/26/2025

    Excellent Doctor visit! Dr. Pacifici was very generous with his time. He accommodated an extensive delay on my part arriving very late by being on route during Emory shooting Incident lockdown. He was extremely easy to converse with regarding my transition from osteopenia to osterperosis. He had very thoroughly previewed all my pertinent records and he detailed all options moving forward. He was very pleasant and conversational and even showed interest in my personal hobbies.I feel confident I am in the best of care!Thank you, Dr Pacifici !

    5 out of 5 stars
    Reviewed on 8/16/2025

    Dr. Pacifica is outstanding.

    5 out of 5 stars
    Reviewed on 8/9/2025

    Listened to my concerns and gave good advice about my concerns. Always a pleasure!

    5 out of 5 stars
    Reviewed on 6/12/2025

    Dr. Pacifici is very professional, explains everything , very thorough !

    5 out of 5 stars
    Reviewed on 5/1/2025

    Dr. Pacifici is what every doctor should be: caring, attentive, knowledgeable. He truly listened to my concerns. I feel encouraged by my visit with him and hopeful about the treatment plan that he proposed.

    5 out of 5 stars
    Reviewed on 4/20/2025

    I have been very please with the care provided by Dr. Pacifici over the years and plan to continue seeing him.

    5 out of 5 stars
    Reviewed on 4/12/2025

    All was very good! I did make my appointment last Fall and couldn't get in until April, but it really was worth the wait, so I am not complaining. Overall, a fantastic experience. (And that is an amazing thing to say about a doctor's visit!)

    5 out of 5 stars
    Reviewed on 4/3/2025

    He looked at the test results carefully and explained the underlying issues very clearly. Ordered new blood test which was needed

    5 out of 5 stars
    Reviewed on 3/6/2025

    Excellent doctor , would definitely recommend him to others.

    5 out of 5 stars
    Reviewed on 3/6/2025

    Very professional showing knowledge and accuracy

    5 out of 5 stars
    Reviewed on 2/28/2025

    Phenomenal experience - Dr. Pacifici is very thorough, very patient, and very compassionate . Emory is lucky to have him!

    5 out of 5 stars
    Reviewed on 2/27/2025

    A wnderful gentleman.

    5 out of 5 stars
    Reviewed on 1/23/2025

    Dr. Pacifico made me feel like I was in very good hands him and his treatment recommendations.

    5 out of 5 stars
    Reviewed on 1/23/2025

    Dr Pacifici is very caring and helpful

    5 out of 5 stars
    Reviewed on 12/12/2024

    Dr. Pacifici knows from previous communication I have real concerns about the medication prescribed and gave me good reassurance for now and for the future. We are pleased to see good results from it.

    5 out of 5 stars
    Reviewed on 12/10/2024

    Dr. Pacifici is very kind and informative.

    5 out of 5 stars
    Reviewed on 12/6/2024

    I EXPERIENCED HELPFUL KNOWLEDGE PERTAINING TO MY HEALTH.

    5 out of 5 stars
    Reviewed on 11/2/2024

    Dr. Pacifici is the best.

    5 out of 5 stars
    Reviewed on 10/31/2024

    Dr pacifici is conscientious and compassionate .

    5 out of 5 stars
    Reviewed on 10/27/2024

    Dr. Pacifici is always thorough, professional and caring. Highly recommend him to family and friends. He is easy to talk to and answers all my questions and concerns.

    5 out of 5 stars
    Reviewed on 9/14/2024

    I will recommend Dr. Pacific to anyone.

    5 out of 5 stars
    Reviewed on 9/1/2024

    My doctor is excellent. He always spent enough time for the patients problem.

    5 out of 5 stars
    Reviewed on 8/18/2024

    Dr. Pacifici is a compassionate expert who has provided me with excellent care over many years.

    5 out of 5 stars
    Reviewed on 8/16/2024

    Dr. Pacifici satisfied my concern with bloodwork and provided me with clear education that I could understand regarding my concerns. I truly appreciate how he listens and hears my concerns

    5 out of 5 stars
    Reviewed on 8/1/2024

    I felt very comfortable, with Dr Roberto he listened to me and answered my questions with patience and I didn't feel rushed.

    5 out of 5 stars
    Reviewed on 6/29/2024

    Top doctor, very thorough and caring, answers all questions

    5 out of 5 stars
    Reviewed on 6/21/2024

    Dr Pacifici was great. Now I understand why he was highly recommended.

    5 out of 5 stars
    Reviewed on 6/16/2024

    Dr. Pacifici was very knowledgeable and provided excellent advice.

    5 out of 5 stars
    Reviewed on 5/9/2024

    My only concern is my appointment is in one year and I will run out and need to sop my medication 6 weeks before my appointment. I need follow up on what to do at the point I stop my treatment (before my appointment).

    5 out of 5 stars
    Reviewed on 5/3/2024

    Dr. Pacifici answered all my questions, and is informative about the medication I am taking.